The small rural town of St. Agnus was one of the few locations on in the world to never be hit by the first Vitas plague. Due to it's remote location and relatively small traveling population the virus never was able to spread there. In addition, when the virus was first reported, the mayor, Samual Emerson, began to implement a variety of "safety" measures. The first of these was the banning of all travel to the town, a measure which was enforced by a hastily assembled militia mostly consisting primarily of trigger happy rednecks. A second measure involved the quarantine of all individuals who showed any of the diseases symptoms, symptoms which sometimes closely resembled those of other, curable, illnesses. Again a goon patrol enforced this measure, at time dragging individuals who so much as sniffled in public to the Wells Sanitarium. The mayor himself allowed no one into or out of his home, administering his makeshift police force via telephone and radio and thus giving them ample opportunity to abuse their power.

The vitas plague quickly burned itself out but the mayor's paranoia continued. More and more the sanitarium began to resemble a prison, bars were installed on the windows and the doors were barred shut. Two weeks after the plague first broke out, and as the sanitarium reached double capacity, a flu epidemic erupted within various parts of the facility. When reports of the "patient's" symptoms were received by the mayor he cracked, thinking he had a Vitas epidemic on his hands. Immediately he ordered the extermination of all individuals confined within the sanitarium. One hundred fifty eight people were put to death that day.

A week later a government health crew, with the help of the military, entered the town after a short battle with local law enforcement. Upon seeing the horror contained within the Wells sanitarium the director of operations, Colonel Adam Kay, closed down the town, ordering all residents to relocate. Barricades were also set up at the town's parimeters, blocking enterance into the village. Kay ordered the mayor and his cronies rounded up for interrogation. Although Emerson escaped the rest were captured and, after a brief on location trial, executed. The sanitarium was then sealed and the town vacated.

Few have traveled to St. Agnus since its abandonment and those who have returned with conflicting stories. Some say Emerson returned and now lives within the hellish confines of the sanitarium. Other say the town is now infested with ghouls and ghosts, spawned from the souls and bodies of the murdered. And then, of course, there are those who never returned at all.